ASCO Annual Meeting runs June 4-8, 2027 at McCormick Place, drawing more than 38,000 attendees and exhibitors to Chicago's South Side lakefront campus. The five hotels below are the closest bookable options to the convention center, ranked by walking distance. Each entry covers the walk route, nearest CTA stop, and what makes the property worth the premium you will pay during one of Chicago's highest-demand weeks.
Hotels near McCormick Place at a glance
| Hotel | Distance (miles) | Walk (min) | Star rating | Guest score |
|---|---|---|---|---|
| Hyatt Regency McCormick Place Chicago | 0 (connected) | 0 | 4 | 8.5 |
| The Wheeler Mansion | 0.24 | 5 | 4 | 2.0 |
| Chicago South Loop Hotel | 0.77 | 15 | 3 | 8.0 |
| Sonder South Wabash | 0.90 | 18 | 4 | 9.4 |
| Jaslin Hotel | 0.95 | 19 | 3 | 8.8 |
Booking tips for ASCO week
- The ASCO housing block through the official portal typically opens six to eight months before the meeting. Properties inside the block carry negotiated rates and are held until a cutoff date.
- The Hyatt Regency McCormick Place sells out first because of the direct walkway connection. If it is full, the Hampton Inn and Home2 Suites at 123 East Cermak are the next-closest options with a 6-minute taxi.
- June in Chicago runs 60-70°F during the day and can drop to the low 50s at night. Pack a layer if you plan to walk between the South Loop hotels and the convention center.
- CTA Green and Orange Line trains stop at Cermak-McCormick Place station, a 5-minute walk from the convention center's North Building entrance. All five hotels below are within a short ride or walk of that station.
Getting to McCormick Place from each hotel
The Hyatt Regency McCormick Place connects directly to the convention center through an enclosed pedestrian bridge, so you never go outside. That matters during early-morning sessions when Chicago's lake wind is at its worst. From the Wheeler Mansion on South Calumet Avenue, the walk is roughly five minutes south along Calumet to the convention center's North Building entrance. The route is flat and straightforward. The Chicago South Loop Hotel on West 26th Street and the Jaslin Hotel on West Cermak Road are both west of the Dan Ryan Expressway. From either property, the most direct route crosses under the expressway via Cermak Road and then heads east to the convention center. Plan for 15-19 minutes on foot or a 5-minute taxi. Sonder South Wabash on South Wabash Avenue is about 18 minutes on foot heading south on Wabash to Cermak, then east to the convention center entrance.
The hotels
Hyatt Regency McCormick Place Chicago
2233 S Martin Luther King Dr
8.51,408 reviews
5 min walk to Cermak-McCormick Place (Green/Orange)The Hyatt Regency McCormick Place is the only hotel with a direct enclosed walkway into the convention center, making it the top choice for ASCO attendees who want zero outdoor exposure between their room and the meeting halls.
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The Wheeler Mansion
2020 South Calumet Avenue
2.01 reviews
8 min walk to Cermak-McCormick Place (Green/Orange)At 0.24 miles from McCormick Place, the Wheeler Mansion is the second-closest property on this list and the only independent boutique option within a 5-minute walk of the convention center.
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Chicago South Loop Hotel
11 W 26th Street
8.04,167 reviews
12 min walk to Cermak-McCormick Place (Green/Orange)The Chicago South Loop Hotel at 0.77 miles from McCormick Place gives attendees a mid-range option with a guest score of 8.0 and a 15-minute walk to the convention center, useful when the Hyatt and Wheeler Mansion are sold out.
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Sonder South Wabash
1419 South Wabash Avenue
9.4550 reviews
10 min walk to Cermak-McCormick Place (Green/Orange)Sonder South Wabash earns its place as the highest-rated 4-star property within one mile of McCormick Place, and its kitchenette units suit attendees staying the full five days of the meeting.
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Jaslin Hotel
261 West Cermak Rd
8.8287 reviews
5 min walk to Cermak-Chinatown (Red)Jaslin Hotel carries the highest guest score among the 3-star properties within one mile of McCormick Place, and its position on Cermak Road puts it on the direct walking route to the convention center.
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Planning a longer stay? See all our Chicago hotel guides.
Frequently asked questions
Which hotel is closest to McCormick Place for ASCO 2027?＋
The Hyatt Regency McCormick Place Chicago is physically connected to the convention center by an enclosed walkway, making it the closest option with no outdoor walking required. The Wheeler Mansion on South Calumet Avenue is the next closest at 0.24 miles, about a 5-minute walk.
Is there a hotel inside McCormick Place?＋
The Hyatt Regency McCormick Place is attached to the convention center via an enclosed pedestrian bridge. It is not technically inside the building, but the connection means you can move between your room and the meeting halls without going outside.
How do I get from the South Loop hotels to McCormick Place without a taxi?＋
The CTA Green and Orange Lines stop at Cermak-McCormick Place station, which is a 5-minute walk from the convention center's North Building entrance. From the South Loop hotels on this list, the station is reachable in 10-15 minutes on foot. During ASCO week, the CTA also runs additional service on these lines.
When should I book a hotel for ASCO 2027?＋
The ASCO housing portal opens roughly six to eight months before the meeting, which puts it around October or November 2026 for the June 2027 dates. Properties connected to the official block sell out quickly. If you miss the block opening, the hotels within a mile of McCormick Place fill next, so booking as soon as the portal opens is the safest approach.
What is the weather like in Chicago during ASCO week in early June?＋
Early June in Chicago typically runs 60-70°F during the day, with evenings dropping to the low 50s. Rain is possible. If you plan to walk between a South Loop hotel and McCormick Place, bring a light waterproof layer.
Are there extended-stay or suite options close to McCormick Place?＋
Sonder South Wabash on South Wabash Avenue offers kitchenette-equipped units at a 4-star level, 0.90 miles from the convention center. For attendees staying the full five days of the meeting, the in-room kitchen reduces the cost of eating out during a week when restaurant demand around McCormick Place is high.
